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Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor
Polarized epithelial non-human (canine) cell lines stably transfected with human or murine complementary DNA (cDNA) encoding for various efflux transporters (P-gp/MDR1, MRP1, MRP2, and Bcrp1) were used to study transepithelial transport of Lopinavir (LVR) and compare results with the MDCKII-Wild typ...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166960/ https://ncbi.nlm.nih.gov/pubmed/17451894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2007.02.036 |
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