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Aberrant cell cycle checkpoint function and early embryonic death in Chk1(−/−) mice

The recent discovery of checkpoint kinases has suggested the conservation of checkpoint mechanisms between yeast and mammals. In yeast, the protein kinase Chk1 is thought to mediate signaling associated with the DNA damage checkpoint of the cell cycle. However, the function of Chk1 in mammals has re...

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Uloženo v:
Vydáno v:Genes Dev
Hlavní autoři: Takai, Hiroyuki, Tominaga, Kaoru, Motoyama, Noboru, Minamishima, Yohji A., Nagahama, Hiroyasu, Tsukiyama, Tadasuke, Ikeda, Kyoji, Nakayama, Keiko, Nakanishi, Makoto, Nakayama, Kei-ichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2000
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316691/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10859163/
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