Cdc42 controls vascular network assembly through protein kinase Cɩ during embryonic vasculogenesis

OBJECTIVE: To determine the role of Cdc42 in embryonic vasculogenesis and the underlying mechanisms. METHODS AND RESULTS: By using genetically modified mouse embryonic stem (ES) cells, we demonstrate that ablation of the Rho GTPase Cdc42 blocks vascular network assembly during embryoid body (EB) vas...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Qi, Yanmei, Liu, Jie, Wu, Xunwei, Brakebusch, Cord, Leitges, Michael, Han, Yaling, Corbett, Siobhan A., Lowry, Stephen F., Graham, Alan M., Li, Shaohua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166614/
https://ncbi.nlm.nih.gov/pubmed/21659643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.230144
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