Cdc42 controls vascular network assembly through protein kinase Cɩ during embryonic vasculogenesis

OBJECTIVE: To determine the role of Cdc42 in embryonic vasculogenesis and the underlying mechanisms. METHODS AND RESULTS: By using genetically modified mouse embryonic stem (ES) cells, we demonstrate that ablation of the Rho GTPase Cdc42 blocks vascular network assembly during embryoid body (EB) vas...

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Détails bibliographiques
Auteurs principaux: Qi, Yanmei, Liu, Jie, Wu, Xunwei, Brakebusch, Cord, Leitges, Michael, Han, Yaling, Corbett, Siobhan A., Lowry, Stephen F., Graham, Alan M., Li, Shaohua
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166614/
https://ncbi.nlm.nih.gov/pubmed/21659643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.230144
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