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Cdc42 controls vascular network assembly through protein kinase Cɩ during embryonic vasculogenesis
OBJECTIVE: To determine the role of Cdc42 in embryonic vasculogenesis and the underlying mechanisms. METHODS AND RESULTS: By using genetically modified mouse embryonic stem (ES) cells, we demonstrate that ablation of the Rho GTPase Cdc42 blocks vascular network assembly during embryoid body (EB) vas...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166614/ https://ncbi.nlm.nih.gov/pubmed/21659643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.230144 |
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