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K-ras is an essential gene in the mouse with partial functional overlap with N-ras
Mammalian ras genes are thought to be critical in the regulation of cellular proliferation and differentiation and are mutated in ∼30% of all human tumors. However, N-ras and H-ras are nonessential for mouse development. To characterize the normal role of K-ras in growth and development, we have mut...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316567/ https://ncbi.nlm.nih.gov/pubmed/9334313 |
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