Ku complex interacts with and stimulates the Werner protein

Werner syndrome (WS) is the hallmark premature aging disorder in which affected humans appear older than their chronological age. The protein WRNp, defective in WS, has helicase function, DNA-dependent ATPase, and exonuclease activity. Although WRNp functions in nucleic acid metabolism, there is lit...

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Foilsithe in:Genes Dev
Main Authors: Cooper, Marcus P., Machwe, Amrita, Orren, David K., Brosh, Robert M., Ramsden, Dale, Bohr, Vilhelm A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2000
Ábhair:
Research Communication
Rochtain Ar Líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316545/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10783163/
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