Ku complex interacts with and stimulates the Werner protein

Werner syndrome (WS) is the hallmark premature aging disorder in which affected humans appear older than their chronological age. The protein WRNp, defective in WS, has helicase function, DNA-dependent ATPase, and exonuclease activity. Although WRNp functions in nucleic acid metabolism, there is lit...

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Bibliografiske detaljer
Main Authors: Cooper, Marcus P., Machwe, Amrita, Orren, David K., Brosh, Robert M., Ramsden, Dale, Bohr, Vilhelm A.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2000
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316545/
https://ncbi.nlm.nih.gov/pubmed/10783163
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