Ku complex interacts with and stimulates the Werner protein

Werner syndrome (WS) is the hallmark premature aging disorder in which affected humans appear older than their chronological age. The protein WRNp, defective in WS, has helicase function, DNA-dependent ATPase, and exonuclease activity. Although WRNp functions in nucleic acid metabolism, there is lit...

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Detalhes bibliográficos
Main Authors: Cooper, Marcus P., Machwe, Amrita, Orren, David K., Brosh, Robert M., Ramsden, Dale, Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316545/
https://ncbi.nlm.nih.gov/pubmed/10783163
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