Continuous Local Delivery of Interferon-β Stabilizes Tumor Vasculature in an Orthotopic Glioblastoma Xenograft Resection Model

BACKGROUND: High-grade glioblastomas have immature, leaky tumor blood vessels that impede the efficacy of adjuvant therapy. We assessed the ability of human interferon-beta (hIFN-β) delivered locally via gene transfer to effect vascular stabilization in an orthotopic glioblastoma xenograft resection...

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Detaylı Bibliyografya
Asıl Yazarlar: Denbo, Jason W., Williams, Regan F., Orr, W. Shannon, Sims, Thomas L., Ng, Catherine Y., Zhou, Junfang, Spence, Yunyu, Morton, Christopher L., Nathwani, Amit C., Duntsch, Christopher, Pfeffer, Lawrence M., Davidoff, Andrew M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164960/
https://ncbi.nlm.nih.gov/pubmed/21878236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2011.07.044
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