Continuous Local Delivery of Interferon-β Stabilizes Tumor Vasculature in an Orthotopic Glioblastoma Xenograft Resection Model

BACKGROUND: High-grade glioblastomas have immature, leaky tumor blood vessels that impede the efficacy of adjuvant therapy. We assessed the ability of human interferon-beta (hIFN-β) delivered locally via gene transfer to effect vascular stabilization in an orthotopic glioblastoma xenograft resection...

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書誌詳細
主要な著者: Denbo, Jason W., Williams, Regan F., Orr, W. Shannon, Sims, Thomas L., Ng, Catherine Y., Zhou, Junfang, Spence, Yunyu, Morton, Christopher L., Nathwani, Amit C., Duntsch, Christopher, Pfeffer, Lawrence M., Davidoff, Andrew M.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164960/
https://ncbi.nlm.nih.gov/pubmed/21878236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2011.07.044
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