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Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts

Despite extensive research, little progress has been made in glioblastoma therapy, owing in part to a lack of adequate preclinical in vivo models to study this disease. To mitigate this, primary patient-derived cell lines, which maintain their specific stem-like phenotypes, have replaced established...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Koessinger, Anna L., Koessinger, Dominik, Stevenson, Katrina, Cloix, Catherine, Mitchell, Louise, Nixon, Colin, Gomez-Roman, Natividad, Chalmers, Anthony J., Norman, Jim C., Tait, Stephen W. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7506024/
https://ncbi.nlm.nih.gov/pubmed/32958777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72322-x
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