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A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses

BACKGROUND. Glioblastoma (GBM) is the most common primary brain tumor, with dismal prognosis. The failure of drug–radiation combinations with promising preclinical data to translate into effective clinical treatments may relate to the use of simplified 2-dimensional in vitro GBM cultures. METHODS. W...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Gomez-Roman, Natividad, Stevenson, Katrina, Gilmour, Lesley, Hamilton, Graham, Chalmers, Anthony J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463789/
https://ncbi.nlm.nih.gov/pubmed/27576873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now164
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