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Small-molecule collection and high-throughput colorimetric assay to identify PARP1 inhibitors
During the last few years, Poly(ADP-ribose)Polymerase (PARP) proteins became a very popular target for anti-cancer treatment. Many PARP inhibitors have been generated and tested by pharmacological industry. However, most of them were designed to disrupt the DNA-dependent PARP1 protein activation pat...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164787/ https://ncbi.nlm.nih.gov/pubmed/21870279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-270-0_29 |
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