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The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21(Cip1)-mediated inhibition of cdk2

The high risk human papillomaviruses (HPVs) are associated etiologically with the majority of human cervical carcinomas. These HPVs encode two viral oncoproteins, E6 and E7, which are expressed consistently in cervical cancers. The function of these viral oncoproteins during a productive infection i...

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Detalles Bibliográficos
Publicado en:Genes Dev
Principais autores: Jones, D. Leanne, Alani, Rhoda M., Münger, Karl
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1997
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316455/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9284049/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.16.2101
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