Chaperone Proteins Abrogate Inhibition of the Human Papillomavirus (HPV) E1 Replicative Helicase by the HPV E2 Protein

Human papillomavirus (HPV) DNA replication requires the viral origin recognition protein E2 and the presumptive viral replicative helicase E1. We now report for the first time efficient DNA unwinding by a purified HPV E1 protein. Unwinding depends on a supercoiled DNA substrate, topoisomerase I, sin...

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Bibliografiske detaljer
Main Authors: Lin, Biing Yuan, Makhov, Alexander M., Griffith, Jack D., Broker, Thomas R., Chow, Louise T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC135630/
https://ncbi.nlm.nih.gov/pubmed/12192057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.18.6592-6604.2002
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