Chaperone Proteins Abrogate Inhibition of the Human Papillomavirus (HPV) E1 Replicative Helicase by the HPV E2 Protein

Human papillomavirus (HPV) DNA replication requires the viral origin recognition protein E2 and the presumptive viral replicative helicase E1. We now report for the first time efficient DNA unwinding by a purified HPV E1 protein. Unwinding depends on a supercoiled DNA substrate, topoisomerase I, sin...

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Hlavní autoři: Lin, Biing Yuan, Makhov, Alexander M., Griffith, Jack D., Broker, Thomas R., Chow, Louise T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
DNA Dynamics and Chromosome Structure
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC135630/
https://ncbi.nlm.nih.gov/pubmed/12192057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.18.6592-6604.2002
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