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Chaperone Proteins Abrogate Inhibition of the Human Papillomavirus (HPV) E1 Replicative Helicase by the HPV E2 Protein

Human papillomavirus (HPV) DNA replication requires the viral origin recognition protein E2 and the presumptive viral replicative helicase E1. We now report for the first time efficient DNA unwinding by a purified HPV E1 protein. Unwinding depends on a supercoiled DNA substrate, topoisomerase I, sin...

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Publicado en:Mol Cell Biol
Autores principales: Lin, Biing Yuan, Makhov, Alexander M., Griffith, Jack D., Broker, Thomas R., Chow, Louise T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2002
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135630/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12192057/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.18.6592-6604.2002
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