Chaperone Proteins Abrogate Inhibition of the Human Papillomavirus (HPV) E1 Replicative Helicase by the HPV E2 Protein

Human papillomavirus (HPV) DNA replication requires the viral origin recognition protein E2 and the presumptive viral replicative helicase E1. We now report for the first time efficient DNA unwinding by a purified HPV E1 protein. Unwinding depends on a supercoiled DNA substrate, topoisomerase I, sin...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Lin, Biing Yuan, Makhov, Alexander M., Griffith, Jack D., Broker, Thomas R., Chow, Louise T.
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2002
Subjects:	DNA Dynamics and Chromosome Structure
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135630/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12192057/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.18.6592-6604.2002
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