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The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21(Cip1)-mediated inhibition of cdk2

The high risk human papillomaviruses (HPVs) are associated etiologically with the majority of human cervical carcinomas. These HPVs encode two viral oncoproteins, E6 and E7, which are expressed consistently in cervical cancers. The function of these viral oncoproteins during a productive infection i...

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Hlavní autoři: Jones, D. Leanne, Alani, Rhoda M., Münger, Karl
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC316455/
https://ncbi.nlm.nih.gov/pubmed/9284049
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