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The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21(Cip1)-mediated inhibition of cdk2

The high risk human papillomaviruses (HPVs) are associated etiologically with the majority of human cervical carcinomas. These HPVs encode two viral oncoproteins, E6 and E7, which are expressed consistently in cervical cancers. The function of these viral oncoproteins during a productive infection i...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Jones, D. Leanne, Alani, Rhoda M., Münger, Karl
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316455/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9284049/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.16.2101
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