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Viral E6-E7 Transcription in the Basal Layer of Organotypic Cultures without Apparent p21cip1 Protein Precedes Immortalization of Human Papillomavirus Type 16- and 18-Transfected Human Keratinocytes

Organotypic cultures of human keratinocytes provide a useful model system to study human papillomavirus (HPV)-host cell interactions. In this study, we analyzed organotypic cultures of two HPV type 16 (HPV16) (FK16A and FK16B)- and two HPV18 (FK18A and FK18B)-transfected keratinocyte cell lines thro...

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Autori principali: Steenbergen, Renske D. M., Parker, Jacqueline N., Isern, Sharon, Snijders, Peter J. F., Walboomers, Jan M. M., Meijer, Chris J. L. M., Broker, Thomas R., Chow, Louise T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC109431/
https://ncbi.nlm.nih.gov/pubmed/9420282
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