Human Papillomavirus E6E7-Mediated Adenovirus Cell Killing: Selectivity of Mutant Adenovirus Replication in Organotypic Cultures of Human Keratinocytes

Replication-competent adenoviruses are being investigated as potential anticancer agents. Exclusive virus replication in cancer cells has been proposed as a safety trait to be considered in the design of oncolytic adenoviruses. From this perspective, we have investigated several adenovirus mutants f...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Balagué, Cristina, Noya, Francisco, Alemany, Ramon, Chow, Louise T., Curiel, David T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11462032/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.16.7602-7611.2001
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