Human Papillomavirus E6E7-Mediated Adenovirus Cell Killing: Selectivity of Mutant Adenovirus Replication in Organotypic Cultures of Human Keratinocytes

Replication-competent adenoviruses are being investigated as potential anticancer agents. Exclusive virus replication in cancer cells has been proposed as a safety trait to be considered in the design of oncolytic adenoviruses. From this perspective, we have investigated several adenovirus mutants f...

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Bibliographic Details
Main Authors: Balagué, Cristina, Noya, Francisco, Alemany, Ramon, Chow, Louise T., Curiel, David T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Gene Therapy
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114995/
https://ncbi.nlm.nih.gov/pubmed/11462032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7602-7611.2001
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