Pro- and anti-apoptotic actions of Stat1 versus Stat3 underlie neuroprotective and immunoregulatory functions of interleukin-11.

Current therapies for the autoimmune demyelinating disease multiple sclerosis (MS) target inflammation but do not directly address oligodendrocyte protection or myelin repair. The gp130 family cytokines CNTF, LIF and IL-11 have been identified as oligodendrocyte growth factors, and IL-11 is also str...

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Hlavní autoři: Zhang, Jingya, Zhang, Yueting, Dutta, Dipankar J., Argaw, Azeb T., Bonnamain, Virginie, Seto, Jeremy, Braun, David A., Zameer, Andleeb, Hayot, Fernand, Lòpez, Carolina B., Raine, Cedric S., John, Gareth R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164308/
https://ncbi.nlm.nih.gov/pubmed/21709156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004066
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