A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-Specific T-Cell Responses

The vaccinia virus (VACV) C6 protein has sequence similarities with the poxvirus family Pox_A46, involved in regulation of host immune responses, but its role is unknown. Here, we have characterized the C6 protein and its effects in virus replication, innate immune sensing and immunogenicity in vivo...

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Detalhes bibliográficos
Main Authors: García-Arriaza, Juan, Nájera, José Luis, Gómez, Carmen E., Tewabe, Nolawit, Sorzano, Carlos Oscar S., Calandra, Thierry, Roger, Thierry, Esteban, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164197/
https://ncbi.nlm.nih.gov/pubmed/21909386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024244
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