Deletion of Vaccinia Virus A40R Gene Improves the Immunogenicity of the HIV-1 Vaccine Candidate MVA-B

Development of a safe and efficacious vaccine against the HIV/AIDS pandemic remains a major scientific goal. We previously described an HIV/AIDS vaccine based on the modified vaccinia virus Ankara (MVA) expressing HIV-1 gp120 and Gag-Pol-Nef (GPN) of clade B (termed MVA-B), which showed moderate imm...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Pérez, Patricia, Marín, María Q., Lázaro-Frías, Adrián, Sorzano, Carlos Óscar S., Gómez, Carmen E., Esteban, Mariano, García-Arriaza, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158668/
https://ncbi.nlm.nih.gov/pubmed/32041218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8010070
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