Improving Adaptive and Memory Immune Responses of an HIV/AIDS Vaccine Candidate MVA-B by Deletion of Vaccinia Virus Genes (C6L and K7R) Blocking Interferon Signaling Pathways

Poxvirus vector Modified Vaccinia Virus Ankara (MVA) expressing HIV-1 Env, Gag, Pol and Nef antigens from clade B (termed MVA-B) is a promising HIV/AIDS vaccine candidate, as confirmed from results obtained in a prophylactic phase I clinical trial in humans. To improve the immunogenicity elicited by...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: García-Arriaza, Juan, Arnáez, Pilar, Gómez, Carmen E., Sorzano, Carlos Óscar S., Esteban, Mariano
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694958/
https://ncbi.nlm.nih.gov/pubmed/23826170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066894
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky