Deletion of the Viral Anti-Apoptotic Gene F1L in the HIV/AIDS Vaccine Candidate MVA-C Enhances Immune Responses against HIV-1 Antigens

Vaccinia virus (VACV) encodes an anti-apoptotic Bcl-2-like protein F1 that acts as an inhibitor of caspase-9 and of the Bak/Bax checkpoint but the role of this gene in immune responses is not known. Because dendritic cells that have phagocytosed apoptotic infected cells cross-present viral antigens...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Perdiguero, Beatriz, Gómez, Carmen Elena, Nájera, Jose Luis, Sorzano, Carlos Oscar S., Delaloye, Julie, González-Sanz, Rubén, Jiménez, Victoria, Roger, Thierry, Calandra, Thierry, Pantaleo, Giuseppe, Esteban, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485360/
https://ncbi.nlm.nih.gov/pubmed/23119046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048524
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados