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The HIV/AIDS Vaccine Candidate MVA-B Administered as a Single Immunogen in Humans Triggers Robust, Polyfunctional, and Selective Effector Memory T Cell Responses to HIV-1 Antigens

Attenuated poxvirus vectors expressing human immunodeficiency virus type 1 (HIV-1) antigens are considered promising HIV/AIDS vaccine candidates. Here, we describe the nature of T cell immune responses induced in healthy volunteers participating in a phase I clinical trial in Spain after intramuscul...

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Hlavní autoři: Gómez, Carmen Elena, Nájera, José Luis, Perdiguero, Beatriz, García-Arriaza, Juan, Sorzano, Carlos Oscar S., Jiménez, Victoria, González-Sanz, Rubén, Jiménez, José Luis, Muñoz-Fernández, María Angeles, López Bernaldo de Quirós, Juan Carlos, Guardo, Alberto C., García, Felipe, Gatell, José M., Plana, Montserrat, Esteban, Mariano
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194965/
https://ncbi.nlm.nih.gov/pubmed/21865377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05165-11
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