Biological Activity of CXCL8 Forms Generated by Alternative Cleavage of the Signal Peptide or by Aminopeptidase-Mediated Truncation

BACKGROUND: Posttranslational modification of chemokines is one of the mechanisms that regulate leukocyte migration during inflammation. Multiple natural NH(2)-terminally truncated forms of the major human neutrophil attractant interleukin-8 or CXCL8 have been identified. Although differential activ...

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Detalhes bibliográficos
Main Authors: Mortier, Anneleen, Berghmans, Nele, Ronsse, Isabelle, Grauwen, Karolien, Stegen, Steve, Van Damme, Jo, Proost, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164136/
https://ncbi.nlm.nih.gov/pubmed/21904597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023913
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