Angiostatic, tumor inflammatory and anti-tumor effects of CXCL4(47–70) and CXCL4L1(47–70) in an EGF-dependent breast cancer model

CXCL4 and CXCL4L1, platelet-derived CXC chemokines, and their carboxy-terminal peptides CXCL4(47–70) and CXCL4L1(47–70) previously displayed angiostatic and anti-tumoral activity in a melanoma model. Here, we found CXCL4(47–70) and CXCL4L1(47–70) to inhibit lymphatic endothelial cell proliferation i...

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Publicat a:Oncotarget
Autors principals: Van Raemdonck, Katrien, Berghmans, Nele, Vanheule, Vincent, Bugatti, Antonella, Proost, Paul, Opdenakker, Ghislain, Presta, Marco, Van Damme, Jo, Struyf, Sofie
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279419/
https://ncbi.nlm.nih.gov/pubmed/25373734
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