Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation

Biological functions of proteins are influenced by posttranslational modifications such as on/off switching by phosphorylation and modulation by glycosylation. Proteolytic processing regulates cytokine and chemokine activities. In this study, we report that natural posttranslational citrullination o...

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Detalhes bibliográficos
Main Authors: Proost, Paul, Loos, Tamara, Mortier, Anneleen, Schutyser, Evemie, Gouwy, Mieke, Noppen, Samuel, Dillen, Chris, Ronsse, Isabelle, Conings, René, Struyf, Sofie, Opdenakker, Ghislain, Maudgal, Prabhat C., Van Damme, Jo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526203/
https://ncbi.nlm.nih.gov/pubmed/18710930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080305
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