Posttranslational Modification of the NH(2)-terminal Region of CXCL5 by Proteases or Peptidylarginine Deiminases (PAD) Differently Affects Its Biological Activity

Posttranslational modifications, e.g. proteolysis, glycosylation, and citrullination regulate chemokine function, affecting leukocyte migration during inflammatory responses. Here, modification of CXCL5/epithelial cell-derived neutrophil-activating protein-78 (ENA-78) by proteases or peptidylarginin...

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Detalhes bibliográficos
Main Authors: Mortier, Anneleen, Loos, Tamara, Gouwy, Mieke, Ronsse, Isabelle, Van Damme, Jo, Proost, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943270/
https://ncbi.nlm.nih.gov/pubmed/20630876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.119388
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