The Positively Charged COOH-terminal Glycosaminoglycan-binding CXCL9(74–103) Peptide Inhibits CXCL8-induced Neutrophil Extravasation and Monosodium Urate Crystal-induced Gout in Mice

The ELR(−)CXC chemokine CXCL9 is characterized by a long, highly positively charged COOH-terminal region, absent in most other chemokines. Several natural leukocyte- and fibroblast-derived COOH-terminally truncated CXCL9 forms missing up to 30 amino acids were identified. To investigate the role of...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Vanheule, Vincent, Janssens, Rik, Boff, Daiane, Kitic, Nikola, Berghmans, Nele, Ronsse, Isabelle, Kungl, Andreas J., Amaral, Flavio Almeida, Teixeira, Mauro Martins, Van Damme, Jo, Proost, Paul, Mortier, Anneleen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571860/
https://ncbi.nlm.nih.gov/pubmed/26183778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649855
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