Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition

Phosphorylation of transcription factors is a key link between cell signaling and the control of gene expression. Here we report that phosphorylation regulates DNA binding of the Ets-1 transcription factor by reinforcing an autoinhibitory mechanism. Quantitative DNA-binding assays show that calcium-...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Cowley, Dale O., Graves, Barbara J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2000
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC316366/
https://ncbi.nlm.nih.gov/pubmed/10673508
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