A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection

BACKGROUND: Dopamine-synthesizing (dopaminergic, DA) neurons in the ventral midbrain (VM) constitute a pivotal neuronal population controlling motor behaviors, cognitive and affective brain functions, which generation critically relies on the activation of Wingless-type MMTV integration site (Wnt)/β...

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Detalhes bibliográficos
Main Authors: L'Episcopo, Francesca, Serapide, Maria F, Tirolo, Cataldo, Testa, Nunzio, Caniglia, Salvatore, Morale, Maria C, Pluchino, Stefano, Marchetti, Bianca
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162575/
https://ncbi.nlm.nih.gov/pubmed/21752258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-49
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