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Uncovering novel actors in astrocyte–neuron crosstalk in Parkinson’s disease: the Wnt/β-catenin signaling cascade as the common final pathway for neuroprotection and self-repair

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by progressive loss of dopaminergic (DAergic) neuronal cell bodies in the substantia nigra pars compacta and gliosis. The cause and mechanisms underlying the demise of nigrostriatal DAergic neurons are ill-defined, but int...

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Detalhes bibliográficos
Main Authors: Marchetti, Bianca, L’Episcopo, Francesca, Morale, Maria Concetta, Tirolo, Cataldo, Testa, Nuccio, Caniglia, Salvo, Serapide, Maria Francesca, Pluchino, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660182/
https://ncbi.nlm.nih.gov/pubmed/23461676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12166
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