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GagCM9-Specific CD8(+) T Cells Expressing Limited Public TCR Clonotypes Do Not Suppress SIV Replication In Vivo
Several lines of evidence suggest that HIV/SIV-specific CD8(+) T cells play a critical role in the control of viral replication. Recently we observed high levels of viremia in Indian rhesus macaques vaccinated with a segment of SIVmac239 Gag (Gag(45–269)) that were subsequently infected with SIVsmE6...
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162554/ https://ncbi.nlm.nih.gov/pubmed/21887264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023515 |
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