Public clonotype usage identifies protective Gag-specific CD8(+) T cell responses in SIV infection

Despite the pressing need for an AIDS vaccine, the determinants of protective immunity to HIV remain concealed within the complexity of adaptive immune responses. We dissected immunodominant virus-specific CD8(+) T cell populations in Mamu-A*01(+) rhesus macaques with primary SIV infection to elucid...

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Detalhes bibliográficos
Main Authors: Price, David A., Asher, Tedi E., Wilson, Nancy A., Nason, Martha C., Brenchley, Jason M., Metzler, Ian S., Venturi, Vanessa, Gostick, Emma, Chattopadhyay, Pratip K., Roederer, Mario, Davenport, Miles P., Watkins, David I., Douek, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715115/
https://ncbi.nlm.nih.gov/pubmed/19349463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081127
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