Public clonotype usage identifies protective Gag-specific CD8(+) T cell responses in SIV infection

Despite the pressing need for an AIDS vaccine, the determinants of protective immunity to HIV remain concealed within the complexity of adaptive immune responses. We dissected immunodominant virus-specific CD8(+) T cell populations in Mamu-A*01(+) rhesus macaques with primary SIV infection to elucid...

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Autores principales: Price, David A., Asher, Tedi E., Wilson, Nancy A., Nason, Martha C., Brenchley, Jason M., Metzler, Ian S., Venturi, Vanessa, Gostick, Emma, Chattopadhyay, Pratip K., Roederer, Mario, Davenport, Miles P., Watkins, David I., Douek, Daniel C.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715115/
https://ncbi.nlm.nih.gov/pubmed/19349463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081127
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