Escape from highly effective public CD8(+) T-cell clonotypes by HIV

Mapping the precise determinants of T-cell efficacy against viruses in humans is a public health priority with crucial implications for vaccine design. To inform this effort, we performed a comprehensive analysis of the effective CD8(+) T-cell clonotypes that constitute responses specific for the HI...

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Autori principali: Iglesias, Maria Candela, Almeida, Jorge R., Fastenackels, Solène, van Bockel, David J., Hashimoto, Masao, Venturi, Vanessa, Gostick, Emma, Urrutia, Alejandra, Wooldridge, Linda, Clement, Mathew, Gras, Stéphanie, Wilmann, Pascal G., Autran, Brigitte, Moris, Arnaud, Rossjohn, Jamie, Davenport, Miles P., Takiguchi, Masafumi, Brander, Christian, Douek, Daniel C., Kelleher, Anthony D., Price, David A., Appay, Victor
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
Soggetti:
Immunobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162351/
https://ncbi.nlm.nih.gov/pubmed/21734237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-328781
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