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Retinal Degeneration Progression Changes Lentiviral Vector Cell Targeting in the Retina

In normal mice, the lentiviral vector (LV) is very efficient to target the RPE cells, but transduces retinal neurons well only during development. In the present study, the tropism of LV has been investigated in the degenerating retina of mice, knowing that the retina structure changes during degene...

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Detalhes bibliográficos
Main Authors: Calame, Maritza, Cachafeiro, Maité, Philippe, Stéphanie, Schouwey, Karine, Tekaya, Meriem, Wanner, Dana, Sarkis, Chamsy, Kostic, Corinne, Arsenijevic, Yvan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161995/
https://ncbi.nlm.nih.gov/pubmed/21901134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023782
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