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Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins
The epigenetic regulator Bmi1 controls proliferation in many organs. Reexpression of cell cycle proteins such as cyclin-dependent kinases (CDKs) is a hallmark of neuronal apoptosis in neurodegenerative diseases. Here we address the potential role of Bmi1 as a key regulator of cell cycle proteins dur...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3574927/ https://ncbi.nlm.nih.gov/pubmed/23359713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108297110 |
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