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Bmi1 Loss Produces an Increase in Astroglial Cells and a Decrease in Neural Stem Cell Population and Proliferation

The polycomb transcriptional repressor Bmi1 promotes cell cycle progression, controls cell senescence, and is implicated in brain development. Loss of Bmi1 leads to a decreased brain size and causes progressive ataxia and epilepsy. Recently, Bmi1 was shown to control neural stem cell (NSC) renewal....

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Zencak, Dusan, Lingbeek, Merel, Kostic, Corinne, Tekaya, Meriem, Tanger, Ellen, Hornfeld, Dana, Jaquet, Muriel, Munier, Francis L., Schorderet, Daniel F., van Lohuizen, Maarten, Arsenijevic, Yvan
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724881/
https://ncbi.nlm.nih.gov/pubmed/15958744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3452-04.2005
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