Bmi1 Loss Produces an Increase in Astroglial Cells and a Decrease in Neural Stem Cell Population and Proliferation

The polycomb transcriptional repressor Bmi1 promotes cell cycle progression, controls cell senescence, and is implicated in brain development. Loss of Bmi1 leads to a decreased brain size and causes progressive ataxia and epilepsy. Recently, Bmi1 was shown to control neural stem cell (NSC) renewal....

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Detalhes bibliográficos
Publicado no:J Neurosci
Principais autores: Zencak, Dusan, Lingbeek, Merel, Kostic, Corinne, Tekaya, Meriem, Tanger, Ellen, Hornfeld, Dana, Jaquet, Muriel, Munier, Francis L., Schorderet, Daniel F., van Lohuizen, Maarten, Arsenijevic, Yvan
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Development/Plasticity/Repair
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724881/
https://ncbi.nlm.nih.gov/pubmed/15958744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3452-04.2005
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