Influence of insulators on transgene expression from integrating and non-integrating lentiviral vectors

BACKGROUND: The efficacy and biosafety of lentiviral gene transfer is influenced by the design of the vector. To this end, properties of lentiviral vectors can be modified by using cis-acting elements such as the modification of the U3 region of the LTR, the incorporation of the central flap (cPPT-C...

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Detalhes bibliográficos
Main Authors: Grandchamp, Nicolas, Henriot, Dorothée, Philippe, Stéphanie, Amar, Lahouari, Ursulet, Suzanna, Serguera, Che, Mallet, Jacques, Sarkis, Chamsy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025823/
https://ncbi.nlm.nih.gov/pubmed/21205311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-9-1
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