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A new mouse model for retinal degeneration due to Fam161a deficiency
FAM161A mutations are the most common cause of inherited retinal degenerations in Israel. We generated a knockout (KO) mouse model, Fam161a(tm1b/tm1b), lacking the major exon #3 which was replaced by a construct that include LacZ under the expression of the Fam161a promoter. LacZ staining was eviden...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7820261/ https://ncbi.nlm.nih.gov/pubmed/33479377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81414-1 |
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