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Efficient Detection of Proteins Retro-Translocated from the ER to the Cytosol by In Vivo Biotinylation

Retro-translocation from the ER to the cytosol of proteins within the secretory pathway takes place on misfolded molecules that are targeted for degradation by the cytosolically located 26S proteasome complex. Retro-translocation occurs also for other proteins (such as calreticulin) that, despite be...

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Main Authors: Petris, Gianluca, Vecchi, Lara, Bestagno, Marco, Burrone, Oscar R.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161056/
https://ncbi.nlm.nih.gov/pubmed/21887304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023712
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