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Selective Targeting of Proteins within Secretory Pathway for Endoplasmic Reticulum-associated Degradation

The endoplasmic reticulum-associated degradation (ERAD) is a cellular quality control mechanism to dispose of misfolded proteins of the secretory pathway via proteasomal degradation. SEL1L is an ER-resident protein that participates in identification of misfolded molecules as ERAD substrates, theref...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vecchi, Lara, Petris, Gianluca, Bestagno, Marco, Burrone, Oscar R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370184/
https://ncbi.nlm.nih.gov/pubmed/22523070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.355107
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