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Native state interconversion of a metamorphic protein requires global unfolding
Lymphotactin (Ltn) is a unique chemokine that under physiological solution conditions displays large-scale structural heterogeneity, defining a new category of ‘metamorphic proteins’. Previous Ltn studies have indicated that each form is required for proper function, but the mechanism of interconver...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160782/ https://ncbi.nlm.nih.gov/pubmed/21776971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200750k |
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