Nalaganje...
Evolution of Fold-Switching in a Metamorphic Protein
Metamorphic proteins switch between different folds, defying the protein folding paradigm. It is unclear how fold-switching arises during evolution. Using ancestral reconstruction and NMR, we studied the evolution of the metamorphic protein XCL1, which has two distinct folds with different functions...
Shranjeno v:
| izdano v: | Science |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8017559/ https://ncbi.nlm.nih.gov/pubmed/33384377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abd8700 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|