Načítá se...
Evolution of Fold-Switching in a Metamorphic Protein
Metamorphic proteins switch between different folds, defying the protein folding paradigm. It is unclear how fold-switching arises during evolution. Using ancestral reconstruction and NMR, we studied the evolution of the metamorphic protein XCL1, which has two distinct folds with different functions...
Uloženo v:
| Vydáno v: | Science |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2021
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8017559/ https://ncbi.nlm.nih.gov/pubmed/33384377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abd8700 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|