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Specific binding-induced modulation of the XCL1 metamorphic equilibrium
The metamorphic protein XCL1 switches between two distinct native structures with different functions in the human immune system. This structural interconversion requires complete rearrangement of all hydrogen bonding networks, yet fold-switching occurs spontaneously and reversibly in solution. One...
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| Gepubliceerd in: | Biopolymers |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8004533/ https://ncbi.nlm.nih.gov/pubmed/32986858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.23402 |
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