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Specific binding-induced modulation of the XCL1 metamorphic equilibrium

The metamorphic protein XCL1 switches between two distinct native structures with different functions in the human immune system. This structural interconversion requires complete rearrangement of all hydrogen bonding networks, yet fold-switching occurs spontaneously and reversibly in solution. One...

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Detalhes bibliográficos
Publicado no:Biopolymers
Main Authors: Dishman, Acacia F., Peterson, Francis C., Volkman, Brian F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004533/
https://ncbi.nlm.nih.gov/pubmed/32986858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.23402
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