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Interconversion between two unrelated protein folds in the lymphotactin native state
Proteins often have multiple functional states, which might not always be accommodated by a single fold. Lymphotactin (Ltn) adopts two distinct structures in equilibrium, one corresponding to the canonical chemokine fold consisting of a monomeric three-stranded β-sheet and carboxyl-terminal helix. T...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278211/ https://ncbi.nlm.nih.gov/pubmed/18364395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709518105 |
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